Human IL-13Ra2 Protein 4565

Additional Information:
accession Q14627|express systemHEK293|product tagC-hFc|purity> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC|backgroundTwo type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ‘ or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ‘, is now referred to as IL-13 R alpha 2.|molecular weightThe protein has a predicted MW of 63.7 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.|available size100 g, 500 g|endotoxinLess than 1EU per g by the LAL method.|Human IL-13Ra2 Protein 4565proteinSize and concentration100, 500g and lyophilizedFormLyophilizedStorage InstructionsValid for 12 months from date of receipt when stored at -80C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.Storage bufferShipped at ambient temperature.Purity> 95% as determined by Tris-Bis PAGEtarget relevanceTwo type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ‘ or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ‘, is now referred to as IL-13 R alpha 2.Protein namesInterleukin-13 receptor subunit alpha-2 (IL-13 receptor subunit alpha-2) (IL-13R subunit alpha-2) (IL-13R-alpha-2) (IL-13RA2) (Interleukin-13-binding protein) (CD antigen CD213a2)Gene namesIL13RA2,IL13RA2 IL13RProtein familyType I cytokine receptor family, Type 5 subfamilyMass9606DaFunctionBinds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4).Subellular locationMembrane; Single-pass type I membrane protein.DomainThTarget Relevance information above includes information from UniProt accession: Q14627The UniProt Consortium|