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Sufficient proof has shown that estrogen and anti-estrogen brokers, this kind of as tamoxifen and fulvestrant, can especially bind to the ligand binding area of estrogen receptor a (Period) to modulate differential expression of downstream transcriptional targets

Blots have been probed with anti-phospho-NF-kB p65 (Ser-536), anti-NF-kB p65, anti-phospho-JNK, anti-JNK, antiphospho-Erk 1/two,...