Product Name :
Gastrofensin AN 5 free base
Description:
Gastrofensin AN 5 free base, a 4-phenyl-tetrahydroisoquinoline derivative, is an antiulcer agent.
CAS:
89845-16-9
Molecular Weight:
344.84
Formula:
C19H21ClN2O2
Chemical Name:
ethyl N-[4-(4-chlorophenyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-8-yl]carbamate
Smiles :
CCOC(=O)NC1=CC=CC2C(CN(C)CC=21)C1C=CC(Cl)=CC=1
InChiKey:
FPTRJSPPLNSVIB-UHFFFAOYSA-N
InChi :
InChI=1S/C19H21ClN2O2/c1-3-24-19(23)21-18-6-4-5-15-16(11-22(2)12-17(15)18)13-7-9-14(20)10-8-13/h4-10,16H,3,11-12H2,1-2H3,(H,21,23)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Gastrofensin AN 5 free base, a 4-phenyl-tetrahydroisoquinoline derivative, is an antiulcer agent.|Product information|CAS Number: 89845-16-9|Molecular Weight: 344.84|Formula: C19H21ClN2O2|Chemical Name: ethyl N-[4-(4-chlorophenyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-8-yl]carbamate|Smiles: CCOC(=O)NC1=CC=CC2C(CN(C)CC=21)C1C=CC(Cl)=CC=1|InChiKey: FPTRJSPPLNSVIB-UHFFFAOYSA-N|InChi: InChI=1S/C19H21ClN2O2/c1-3-24-19(23)21-18-6-4-5-15-16(11-22(2)12-17(15)18)13-7-9-14(20)10-8-13/h4-10,16H,3,11-12H2,1-2H3,(H,21,23)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.18:0 mPEG2000 PE Description |Shelf Life: ≥12 months if stored properly.Isorhamnetin PI3K/Akt/mTOR |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33254278 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Gastrofensin AN 5 supresses the formation of ulcers in all experimental models. From the broad pharmacological studies of Gastrofensin AN 5 on this model it can be seen that even a dose of 0.100 mg/kg has a high antiulcer activity. The increase of the dose leads to a regular increase of the antiulcer activity, the highest suppression of the ulcer index being reaches at a dose of 1 mg/kg (86.15%). The comparative studies with Ranitidine and Cimetidine on the same experimental models of gastric ulcers show that Gastrofensin AN 5 possesses an antiulcer activity many times higher than that of the above-mentioned drugs.|Products are for research use only. Not for human use.|
